Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (29): 5489-5492.doi: 10.3969/j.issn. 2095-4344.2012.29. 035

Previous Articles     Next Articles

New charged calcium sulfate/beta-tricalcium phosphate compound bone cement for unilateral and bilateral transpedicular vertebroplasty: Bone cement leakage and biomechanics changes

Qin Yi1, 2, Jiang Jian-ming1, Zhu Qing-an1, Qu Dong-bin1, Yang Yong1, Liu Peng1   

  1. 1Department of Spinal Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 501515, Guangdong Province, China;
    2Second Department of Orthopedics and Traumatology, Zhuhai Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine, Zhuhai 519020, Guangdong Province, China
  • Received:2012-03-02 Revised:2012-05-07 Online:2012-07-15 Published:2012-07-15
  • Contact: Jiang Jian-ming, Professor, Doctoral supervisor, Department of Spinal Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 501515, Guangdong Province, China jjm19991999@ sohu.com
  • About author:Qin Yi☆, Studying for doctorate, Attending physician, Department of Spinal Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 501515, Guangdong Province, China; Second Department of Orthopedics and Traumatology, Zhuhai Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine, Zhuhai 519020, Guangdong Province, China qinyi0225@163.com

PDF

294

Abstract:

BACKGROUND: A new type of charged calcium sulfate/beta-tricalcium phosphate compound bone cement can restore vertebral mechanical properties, and meanwhile reduce the risk for bone cement leakage in traditional vertebroplasty and improve operation safety.
OBJECTIVE: To study bone cement leakage and vertebral biomechanical changes by observation of the new charged calcium sulfate/beta-tricalcium phosphate compound bone cement in unilateral and bilateral transpedicular vertebroplasty.
METHODS: Osteoporotic thoracolumbar specimens selected from eight old male corpses were used to prepare a vertebral compression fracture model. Two successive vertebral specimens were paired to be cross-assigned into unilateral and bilateral groups. In the unilateral group, 4 mL of new charged calcium sulfate/beta-tricalcium phosphate compound bone cement was applied in unilateral transpedicular vertebroplasty; 4 mL of new charged calcium sulfate/beta-tricalcium phosphate compound bone cement was used for bilateral transpedicular vertebroplasty in the bilateral group, 2 mL at each side.
RESULTS AND CONCLUSION: The leakage volume of bone cement in the unilateral group was significantly higher than that in the bilateral group (P < 0.05). There was no significant difference in the maximum load and stiffness between the two groups (P > 0.05). Bilateral transpedicular vertebroplasty with new charged calcium sulfate/beta-tricalcium phosphate compound bone cement is better, and the decreased volume of injected bone cement helps to reduce the leakage risk of bone cement. However, there is no difference between the vertebral biomechanical changed of the two groups.

CLC Number: